Articles publicats

Universitat de Girona Plana personal del Dr. Marc Ribo Panosa
Informació general
  • 9387 (628453922)
  • marc.ribo@udg.edu
  • EDIFICI AULARI COMÚ - LEAR
    Campus Montilivi
    17003 - GIRONA
    Despatx: L-217
 

Publicacions en revistes

    Abstract
    Vilanova, M., Castro, J., Tubert, P., Ribo, M., Benito, A.   "Ribonucleases directed to the nucleus as a novel proapoptotic anticancer strategy ."  New Biotechnology  25 (2009):  S8-S9.

     

    Article
    Kurpiewska, K.; Torrent, G.; Ribó, M.; Loch, J.I.; Vilanova, M.; Lewiński, K.  "Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution."  Biopolymers (títol associat amb Peptide Science)  101 (2015):  454-460.
    Serrano, S., Callís, M., Vilanova, M., Benito, A., Laurents, D.V., Ribó, M. & Bruix, M.  "1H, 13C and 15N resonance assignments of the Onconase FL-G zymogen."  Biomolecular Nmr Assignments  7 (2013):  13-15.
    Callís, M., Serrano, S., Benito, A., Laurents, Vilanova, M., D.V., Bruix, M.& Ribó, M.   "Towards Tricking a Pathogen’s Protease into Fighting Infection: The 3D Structure of a Stable Circularly Permuted Onconase Variant Cleavedby HIV-1 Protease."  PLoS One  8 (2013):  e54568-e54568.
    Castro, Jessica; Ribó, Marc; Puig, Teresa, Colomer, Ramon, Vilanova, Maria & Benito, Antoni  "A cytotoxic ribonuclease reduces the expression level of P-glycoprotein in multidrug-resistant cell lines ."  Investigational New Drugs  30 (2012):  880-888.
    Vert, A.; Castro, J.; Ruiz-Martínez, S.; Tubert, P., Escribano, D.; Ribó, M.; Vilanova, M.; and Benito, A.  "Generation of New Cytotoxic Human Ribonuclease Variants Directed to the Nucleus."  Molecular Pharmaceutics  9 (2012):  2894-2902.
    Jessica Castro, Marc Ribó, Susanna Navarro, Maria Victòria Nogués, Maria Vilanova and Antoni Benito  "A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation ."  BMC Cancer  11 (2011):  9-.
    Tubert, P., Laurents, D.V., Ribó, M., Bruix, M., Vilanova, M. & Benito, A.  "Interactions crucial for 3D swapping in the HP-RNase variant PM8 ."  Biophysical Journal  101 (2011):  459-467.
    Tubert, Pere; Rodríguez, Montserrat; Ribó, Marc; Benito, Antoni; Vilanova, Maria  "The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity ."  Investigational New Drugs  29 (2011):  811-817.
    Ercole, Carmine; López Alonso, Jorge Pedro; Font, Josep; Ribó, Marc; Vilanova, Maria; Picone, Delia; Laurents, Douglas V.  "Crowding agents and osmolytes provide insight into the formation and dissociation of RNase A oligomers ."  Archives of Biochemistry and Biophysics  506 (2011):  123-129.
    López Alonso, Jorge; Bruix, Marta; Font, Josep; Ribó, Marc; Vilanova, Maria; Jimenez, M. Angeles; Santoro, Jorge; González, Carlos; Laurents, Douglas  "NMR Spectroscopy Reveals that RNase A is Chiefly Denatured in 40% Acetic Acid: Implications for Oligomer Formation by 3D Domain Swapping."  Journal of the American Chemical Society  132 (2010):  1621-1630.
    Torrent, G.; Ribó, M.; Benito, A.; Vilanova, M.  "Bactericidal activity engineered on human pancreatic ribonuclease and onconase ."  Molecular Pharmaceutics  6 (2009):  531-542.
    Marchal, S.; Font, J.; Ribó, M.; Vilanova, M.; Phillips, R.; Lange, R.; Torrent, J.  "Asymmetric kinetics of protein structural changes ."  Accounts of Chemical Research  42 (2009):  778-787.
    López-Alonso, J.P.; Diez-García, F.; Font, J.; Ribó, M.; Vilanova, M.; Scholtz, J.M.; González, C.; Vottariello, F.; Gotte, G.; Libonati, M.; Laurents, D.V.  "Carbodiimide EDC induces cross-links that stabilize RNAse A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation and activity."  Bioconjugate Chemistry  20 (2009):  1459-1473.
    Kurpiewska, K.; Font, J.; Ribó, M.; Vilanova, M.; Lewinski, K.  "X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: Further insight into protein stability ."  Proteins  77 (2009):  658-669.
    Vilà, R.; Benito, A.; Ribó, M.; Vilanova, M.  "Mapping the stability clusters in bovine pancreatic ribonuclease A ."  Biopolymers (títol associat amb Peptide Science)  91 (2009):  1038-1047.
    Bruix, M.; Ribó, M.; Benito, A.; Laurents, D.V.; Rico, M.; Vilanova, M.  "Destabilizing mutations alter the hydrogen exchange mechanism of RNase A ."  Biophysical Journal  94 (2008):  2297-2305.
    Torrent, J.; Marchal, S.; Ribó, M.; Vilanova, M.; Georges, C.; Dupont, Y.; Lange, R.  "Distinct unfolding and refolding pathways of ribonuclease A revealed by heating and cooling temperature jumps ."  Biophysical Journal  94 (2008):  4056-4065.
    Torrent, G.; Benito, A.; Castro, J.; Ribó, M.; Vilanova, M.  "Contribution of the C30/C75 disulfide bond to the biological properties of onconase."  Biological Chemistry Hoppe-Seyler  389 (2008):  1127-1136.
    Benito, A.; Laurents, D.V.; Ribó, M.; Vilanova, M.  "The structural determinants that lead to the formation of particular oligomeric structures in the pancreatic-type ribonuclease family."  Current Protein and Peptide Science  9 (2008):  370-393.
    Benito, A.; Vilanova, M.; Ribó, M.  "Intracellular routing of cytotoxic pancreatic-type ribonucleases ."  Current Pharmaceutical Biotechnology  9 (2008):  169-179.
    Vila-Perelló, M.; Hori, Y.; Ribó, M.; Muir, T.W.  "Activation of protein splicing by protease or light triggered O to N acyl migration ."  Angewandte Chemie International Edition  47 (2008):  7764-7767.
    Rodríguez, M.; Torrent, G.; Bosch, M.; Rayne, F.; Dubremetz, J.F.; Ribó, M.; Benito, A.; Vilanova, M.; Beaumelle, B.   "Intracellular pathway of onconase that enables its delivery to the cytosol ."  Journal of Cell Science  120 (2007):  1405-1411.
    Ribó, M.; Font, J.; Benito, A.; Torrent. J.; Lange, R.; Vilanova, M.  "Pressure as a tool to study protein-unfolding/refolding processes: the case of ribonuclease A ."  Biochimica et Biophysica Acta  1764 (2006):  461-469.
    Torrent, J.; Font, J.; Herberhold, H.; Marchal, S.; Ribó, M.; Ruan, K.; Winter, R.; Vilanova, M; Lange, R.  "The use of pressure-jump relaxation kinetics to study protein folding landscapes ."  Biochimica et Biophysica Acta  1764 (2006):  489-496.
    Font, J.; Benito, A.; Torrent, J.; Lange, R.; Ribó, M.; Vilanova, M.  "Pressure- and temperature-induced unfolding studies:Thermodynamics of core hydrophobicity and packing of ribonuclease A."  Biological Chemistry Hoppe-Seyler  387 (2006):  285-296.
    López-Alonso, J.P.; Bruix, M.; Font, J.; Ribó, M.; Vilanova, M.; Rico, M.; Gotte, G.; Libonati, M.; González, C.; Laurents, D.V.  "Formation, structure, and dissociation of the ribonuclease S three-dimensional domain-swapped dimer."  Journal of Biological Chemistry  281 (2006):  9400-9406.
    Rodríguez, M.; Benito, A.; Ribó, M.; Vilanova, M.  "Characterization of the dimerization process of a domain-swapped dimeric variant of human pancreatic ribonuclease ."   Febs Journal  273 (2006):  1166-1176.
    Font, J.; Benito, A.; Lange, R.; Ribó, M.; Vilanova, M.  "The contribution of the residues from the main hydrophobic core of ribonuclease A to its pressure-folding transition state.."  Protein Science  15 (2006):  1000-1009.
    Rodríguez, M.; Benito, A.; Tubert, P.; Castro, J.; Ribó, M.; Beaumelle, B.; Vilanova, M.  "A cytotoxic ribonuclease variant with a discontinuous nuclear localization signal constituted by basic residues scattered over three areas of the molecule ."  Journal of Molecular Biology  360 (2006):  548-557.
    Font, J.; Torrent, J.; Ribó, M.; Laurents, D.V.; Balny, C.; Vilanova, M.; Lange, R.  "Pressure-jump-induced kinetics reveals a hydration dependent folding/unfolding mechanism of ribonuclease A ."  Biophysical Journal  91 (2006):  2264-2274.
    Nikolovski, Z.; Buzón, V.; Ribó, M.; Moussaoui, M.; Vilanova, M.; Cuchillo, C.M.; Cladera, J.; Nogués, M.V.   "Thermal unfolding of eosinophil cationic protein/ribonuclease 3: a nonreversible process."  Protein Science  15 (2006):  2816-2827.
    Benito, A.; Ribó, M.; Vilanova, M.  "On the track of antitumor ribonucleases."  Molecular Biosystems  1 (2005):  294-302.
    Bosch, M.; Benito, A.; Ribó, M.; Puig, T.; Beaumelle, B.; Vilanova, M.  "A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity."  Biochemistry  43 (2004):  2167-2177.
    Ribó, M.; Bosch, M.; Torrent, G.; Benito, A.; Beaumelle, B.; Vilanova, M.  "Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation process of onconase."  European Journal of Biochemistry  271 (2004):  1163-1171.
    Benito, A.; Bosch, M.; Torrent, G.; Ribó, M.; Vilanova, M.  "Stabilisation of human pancreatic ribonuclease through mutation at its N-terminal edge."  Protein Engineering  15 (2002):  887-893.
    Ribó, M.; Benito, A.; Canals, A.; Nogués, M.V.; Cuchillo, C.M.; Vilanova, M.  "Purification of engineered human pancreatic ribonuclease."  Methods in Enzymology  341 (2001):  221-233.
    Torrent, J.; Rubens, P.; Ribó, M.; Heremans, K.; Vilanova, M.  "Pressure versus temperature-unfolding of ribonuclease A: an FTIR spectroscopic characterization of 10 variants at the carboxy terminal site."  Protein Science  10 (2001):  725-734.
    Canals, A.; Pous, J.; Guasch, A.; Benito, A.; Ribó, M.; Vilanova, M.; Coll, M.  "The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins towards oligomerization ."  Structure  9 (2001):  967-976.
    Pous, J.; Canals, A.; Terzyan, S.S.; Guasch, A.; Benito, A.; Ribó, M.; Vilanova, M.; Coll, M.  "Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the dsign of cytotoxic ribonucleases ."  Journal of Molecular Biology  303 (2000):  49-59.
    Torrent, J.; Connelly, J.P.; Rubens, P.; Coll, M.G,; Ribó, M.; Lange, R.; Heremans, K.; Vilanova, M.   "The response of the C-terminal variants of ribonuclease A to pressure and temperature-induced unfolding. A study by fourth derivative UV and Fourier transform infrared spectroscopy."  High Pressure Research  19 (2000):  247-252.
    Canals, A., Ribó, M., Benito, A., Bosch, M., Mombelli, E. & Vilanova, M.   "Production of engineered human pancreatic ribonucleases, solving expression and purification problems, and enhancing thermostability..."  Protein Expression and Purification  17 (1999):  169-181.
    Torrent, J., Connelly, J.P., Coll, M.G., Ribó, M., Lange, R. & Vilanova, M.   "Pressure versus heat-induced unfolding of ribonuclease A: The case of hydrophobic interactions within a chain folding initiation site.."  Biochemistry  38 (1999):  15952-15961.
    Coll, M.G., Protasevich, I.I., Torrent, J., Ribó, M., Lobachov, V.M., Makarov, A.A. & Vilanova, M.   "Valine 108, a chain folding initiation site belonging residue, crucial for the ribonuclease A stability.."  Biochemical and Biophysical Research Communications  265 (1999):  356-360.
    Nogués, M.V., Moussaoui, M., Boix, E., Vilanova, M. Ribó, M. & Cuchillo, C.M.  "The contribution of noncatalytic phosphate binding subsites to the mechanism of bovine pancreatic ribonuclease A.."  Cellular and Molecular Life Sciences  54 (1998):  766-774.
    Boqué, Ll., Coll, M.G., Ribó, M., Cuchillo, C.M., Fita, I. & Vilanova, M.   "Tridimensional structure of three ribonuclease A covalent derivatives with pyridoxal 5'-phosphate.."  Protein and Peptide Letters  5 (1998):  101-108.
    Matousek, J., Kim, J-S, Soucek, J., Riha, J., Ribó, M., Leland, P.A. and Raines, R.T.  "Ribonucleases endowed with specific toxicity for spermatogenic layers."  Comparative biochemistry and physiology. Part B, Biochemistry and molecular biology  118B (1997):  881-888.
    Ribó, M., delCardayré, S.B., Raines, R. T, Llorens, R and Cuchillo, Claudi M.  "Production of human pancreatic ribonuclease in Saccharomyces cerevisiae and Escherichia coli."  Protein Expression and Purification  7 (1996):  253-256.
    delCardayré, S.B., Ribó, M., Yokel, E.M., Quirk, D.J., Rutter, W. J. and Raines, R. T.  "Ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln 11."  Protein Engineering  8 (1995):  261-273.
    Bravo, J., Fernández, E., Ribó, M., Llorens, R. and Cuchillo C. M.  "A versatile negative staining ribonuclease zymogram."  Analytical Biochemistry  219 (1994):  82-86.
    Ribó, M., Beintema, J. J., Osset, M., Fernández, E., Bravo, J., Llorens, R. and Cuchillo C. M.  "Heterogeneity in the Glycosylation Pattern of Human Pancreatic Ribonuclease. ."  Biological Chemistry Hoppe-Seyler  375 (1994):  357-363.

     

    Proceeding
    M. J. M. Fallon, C. Balagué, E. Fernández, M. Ribó, J. Bravo, R. de Llorens and Claudi M. Cuchillo  "Monoclonal Antibodies to Bovine Pancreatic Ribonuclease."  Structure, Mechanism and Function of Ribonucleases   (1991):  229-234.
    M. Ribó, E. Fernández, J. Bravo, M. Osset, M. J. M. Fallon, R. De Llorens and Claudi M. Cuchillo  "Purification of human pancratic ribonuclease by high performance liquid chromatography."  Structure, Mechanism and Function of Ribonucleases   (1991):  157-162.
    E. Fernández, M. Ribó, J. Bravo, M. Osset, M. J. M. Fallon, R. De Llorens and Claudi M. Cuchillo  "Isolation of secreted enzymes with ribonuclease activity from human pancreatic adenocarcinoma cell line CAPAN-1."  Structure, Mechanism and Function of Ribonucleases   (1991):  163-168.
    J. Bravo, M. J. M. Fallon, M. Ribó, E. Fernández, M. Osset, R. De Llorens and Claudi M. Cuchillo  "PHMB (p-hydroxymercuribenzoate) utilization to inactivate the inhibitor of ribonuclease in normal human pancreatic tissue and tissue culture medium from CAPAN-1 cells."  Structure, Mechanism and Function of Ribonucleases   (1991):  201-206.

     

     

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