Articles publicats

Universitat de Girona Plana personal del Dr. Marc Ribo Panosa
Informació general
  • 9387 (628453922)
    Campus Montilivi
    17003 - GIRONA
    Despatx: L-217

Publicacions en revistes

    Vilanova, M., Castro, J., Tubert, P., Ribo, M., Benito, A.   "Ribonucleases directed to the nucleus as a novel proapoptotic anticancer strategy ."  New Biotechnology  25 (2009):  S8-S9.


    Kurpiewska, K.; Torrent, G.; Ribó, M.; Loch, J.I.; Vilanova, M.; Lewiński, K.  "Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution."  Biopolymers (títol associat amb Peptide Science)  101 (2015):  454-460.
    Serrano, S., Callís, M., Vilanova, M., Benito, A., Laurents, D.V., Ribó, M. & Bruix, M.  "1H, 13C and 15N resonance assignments of the Onconase FL-G zymogen."  Biomolecular Nmr Assignments  7 (2013):  13-15.
    Callís, M., Serrano, S., Benito, A., Laurents, Vilanova, M., D.V., Bruix, M.& Ribó, M.   "Towards Tricking a Pathogen’s Protease into Fighting Infection: The 3D Structure of a Stable Circularly Permuted Onconase Variant Cleavedby HIV-1 Protease."  PLoS One  8 (2013):  e54568-e54568.
    Castro, Jessica; Ribó, Marc; Puig, Teresa, Colomer, Ramon, Vilanova, Maria & Benito, Antoni  "A cytotoxic ribonuclease reduces the expression level of P-glycoprotein in multidrug-resistant cell lines ."  Investigational New Drugs  30 (2012):  880-888.
    Vert, A.; Castro, J.; Ruiz-Martínez, S.; Tubert, P., Escribano, D.; Ribó, M.; Vilanova, M.; and Benito, A.  "Generation of New Cytotoxic Human Ribonuclease Variants Directed to the Nucleus."  Molecular Pharmaceutics  9 (2012):  2894-2902.
    Jessica Castro, Marc Ribó, Susanna Navarro, Maria Victòria Nogués, Maria Vilanova and Antoni Benito  "A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation ."  BMC Cancer  11 (2011):  9-.
    Tubert, P., Laurents, D.V., Ribó, M., Bruix, M., Vilanova, M. & Benito, A.  "Interactions crucial for 3D swapping in the HP-RNase variant PM8 ."  Biophysical Journal  101 (2011):  459-467.
    Tubert, Pere; Rodríguez, Montserrat; Ribó, Marc; Benito, Antoni; Vilanova, Maria  "The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity ."  Investigational New Drugs  29 (2011):  811-817.
    Ercole, Carmine; López Alonso, Jorge Pedro; Font, Josep; Ribó, Marc; Vilanova, Maria; Picone, Delia; Laurents, Douglas V.  "Crowding agents and osmolytes provide insight into the formation and dissociation of RNase A oligomers ."  Archives of Biochemistry and Biophysics  506 (2011):  123-129.
    López Alonso, Jorge; Bruix, Marta; Font, Josep; Ribó, Marc; Vilanova, Maria; Jimenez, M. Angeles; Santoro, Jorge; González, Carlos; Laurents, Douglas  "NMR Spectroscopy Reveals that RNase A is Chiefly Denatured in 40% Acetic Acid: Implications for Oligomer Formation by 3D Domain Swapping."  Journal of the American Chemical Society  132 (2010):  1621-1630.
    Torrent, G.; Ribó, M.; Benito, A.; Vilanova, M.  "Bactericidal activity engineered on human pancreatic ribonuclease and onconase ."  Molecular Pharmaceutics  6 (2009):  531-542.
    Marchal, S.; Font, J.; Ribó, M.; Vilanova, M.; Phillips, R.; Lange, R.; Torrent, J.  "Asymmetric kinetics of protein structural changes ."  Accounts of Chemical Research  42 (2009):  778-787.
    López-Alonso, J.P.; Diez-García, F.; Font, J.; Ribó, M.; Vilanova, M.; Scholtz, J.M.; González, C.; Vottariello, F.; Gotte, G.; Libonati, M.; Laurents, D.V.  "Carbodiimide EDC induces cross-links that stabilize RNAse A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation and activity."  Bioconjugate Chemistry  20 (2009):  1459-1473.
    Kurpiewska, K.; Font, J.; Ribó, M.; Vilanova, M.; Lewinski, K.  "X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: Further insight into protein stability ."  Proteins  77 (2009):  658-669.
    Vilà, R.; Benito, A.; Ribó, M.; Vilanova, M.  "Mapping the stability clusters in bovine pancreatic ribonuclease A ."  Biopolymers (títol associat amb Peptide Science)  91 (2009):  1038-1047.
    Bruix, M.; Ribó, M.; Benito, A.; Laurents, D.V.; Rico, M.; Vilanova, M.  "Destabilizing mutations alter the hydrogen exchange mechanism of RNase A ."  Biophysical Journal  94 (2008):  2297-2305.
    Torrent, J.; Marchal, S.; Ribó, M.; Vilanova, M.; Georges, C.; Dupont, Y.; Lange, R.  "Distinct unfolding and refolding pathways of ribonuclease A revealed by heating and cooling temperature jumps ."  Biophysical Journal  94 (2008):  4056-4065.
    Torrent, G.; Benito, A.; Castro, J.; Ribó, M.; Vilanova, M.  "Contribution of the C30/C75 disulfide bond to the biological properties of onconase."  Biological Chemistry Hoppe-Seyler  389 (2008):  1127-1136.
    Benito, A.; Laurents, D.V.; Ribó, M.; Vilanova, M.  "The structural determinants that lead to the formation of particular oligomeric structures in the pancreatic-type ribonuclease family."  Current Protein and Peptide Science  9 (2008):  370-393.
    Benito, A.; Vilanova, M.; Ribó, M.  "Intracellular routing of cytotoxic pancreatic-type ribonucleases ."  Current Pharmaceutical Biotechnology  9 (2008):  169-179.
    Vila-Perelló, M.; Hori, Y.; Ribó, M.; Muir, T.W.  "Activation of protein splicing by protease or light triggered O to N acyl migration ."  Angewandte Chemie International Edition  47 (2008):  7764-7767.
    Rodríguez, M.; Torrent, G.; Bosch, M.; Rayne, F.; Dubremetz, J.F.; Ribó, M.; Benito, A.; Vilanova, M.; Beaumelle, B.   "Intracellular pathway of onconase that enables its delivery to the cytosol ."  Journal of Cell Science  120 (2007):  1405-1411.
    Ribó, M.; Font, J.; Benito, A.; Torrent. J.; Lange, R.; Vilanova, M.  "Pressure as a tool to study protein-unfolding/refolding processes: the case of ribonuclease A ."  Biochimica et Biophysica Acta  1764 (2006):  461-469.
    Torrent, J.; Font, J.; Herberhold, H.; Marchal, S.; Ribó, M.; Ruan, K.; Winter, R.; Vilanova, M; Lange, R.  "The use of pressure-jump relaxation kinetics to study protein folding landscapes ."  Biochimica et Biophysica Acta  1764 (2006):  489-496.
    Font, J.; Benito, A.; Torrent, J.; Lange, R.; Ribó, M.; Vilanova, M.  "Pressure- and temperature-induced unfolding studies:Thermodynamics of core hydrophobicity and packing of ribonuclease A."  Biological Chemistry Hoppe-Seyler  387 (2006):  285-296.
    López-Alonso, J.P.; Bruix, M.; Font, J.; Ribó, M.; Vilanova, M.; Rico, M.; Gotte, G.; Libonati, M.; González, C.; Laurents, D.V.  "Formation, structure, and dissociation of the ribonuclease S three-dimensional domain-swapped dimer."  Journal of Biological Chemistry  281 (2006):  9400-9406.
    Rodríguez, M.; Benito, A.; Ribó, M.; Vilanova, M.  "Characterization of the dimerization process of a domain-swapped dimeric variant of human pancreatic ribonuclease ."   Febs Journal  273 (2006):  1166-1176.
    Font, J.; Benito, A.; Lange, R.; Ribó, M.; Vilanova, M.  "The contribution of the residues from the main hydrophobic core of ribonuclease A to its pressure-folding transition state.."  Protein Science  15 (2006):  1000-1009.
    Rodríguez, M.; Benito, A.; Tubert, P.; Castro, J.; Ribó, M.; Beaumelle, B.; Vilanova, M.  "A cytotoxic ribonuclease variant with a discontinuous nuclear localization signal constituted by basic residues scattered over three areas of the molecule ."  Journal of Molecular Biology  360 (2006):  548-557.
    Font, J.; Torrent, J.; Ribó, M.; Laurents, D.V.; Balny, C.; Vilanova, M.; Lange, R.  "Pressure-jump-induced kinetics reveals a hydration dependent folding/unfolding mechanism of ribonuclease A ."  Biophysical Journal  91 (2006):  2264-2274.
    Nikolovski, Z.; Buzón, V.; Ribó, M.; Moussaoui, M.; Vilanova, M.; Cuchillo, C.M.; Cladera, J.; Nogués, M.V.   "Thermal unfolding of eosinophil cationic protein/ribonuclease 3: a nonreversible process."  Protein Science  15 (2006):  2816-2827.
    Benito, A.; Ribó, M.; Vilanova, M.  "On the track of antitumor ribonucleases."  Molecular Biosystems  1 (2005):  294-302.
    Bosch, M.; Benito, A.; Ribó, M.; Puig, T.; Beaumelle, B.; Vilanova, M.  "A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity."  Biochemistry  43 (2004):  2167-2177.
    Ribó, M.; Bosch, M.; Torrent, G.; Benito, A.; Beaumelle, B.; Vilanova, M.  "Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation process of onconase."  European Journal of Biochemistry  271 (2004):  1163-1171.
    Benito, A.; Bosch, M.; Torrent, G.; Ribó, M.; Vilanova, M.  "Stabilisation of human pancreatic ribonuclease through mutation at its N-terminal edge."  Protein Engineering  15 (2002):  887-893.
    Ribó, M.; Benito, A.; Canals, A.; Nogués, M.V.; Cuchillo, C.M.; Vilanova, M.  "Purification of engineered human pancreatic ribonuclease."  Methods in Enzymology  341 (2001):  221-233.
    Torrent, J.; Rubens, P.; Ribó, M.; Heremans, K.; Vilanova, M.  "Pressure versus temperature-unfolding of ribonuclease A: an FTIR spectroscopic characterization of 10 variants at the carboxy terminal site."  Protein Science  10 (2001):  725-734.
    Canals, A.; Pous, J.; Guasch, A.; Benito, A.; Ribó, M.; Vilanova, M.; Coll, M.  "The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins towards oligomerization ."  Structure  9 (2001):  967-976.
    Pous, J.; Canals, A.; Terzyan, S.S.; Guasch, A.; Benito, A.; Ribó, M.; Vilanova, M.; Coll, M.  "Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the dsign of cytotoxic ribonucleases ."  Journal of Molecular Biology  303 (2000):  49-59.
    Torrent, J.; Connelly, J.P.; Rubens, P.; Coll, M.G,; Ribó, M.; Lange, R.; Heremans, K.; Vilanova, M.   "The response of the C-terminal variants of ribonuclease A to pressure and temperature-induced unfolding. A study by fourth derivative UV and Fourier transform infrared spectroscopy."  High Pressure Research  19 (2000):  247-252.
    Canals, A., Ribó, M., Benito, A., Bosch, M., Mombelli, E. & Vilanova, M.   "Production of engineered human pancreatic ribonucleases, solving expression and purification problems, and enhancing thermostability..."  Protein Expression and Purification  17 (1999):  169-181.
    Torrent, J., Connelly, J.P., Coll, M.G., Ribó, M., Lange, R. & Vilanova, M.   "Pressure versus heat-induced unfolding of ribonuclease A: The case of hydrophobic interactions within a chain folding initiation site.."  Biochemistry  38 (1999):  15952-15961.
    Coll, M.G., Protasevich, I.I., Torrent, J., Ribó, M., Lobachov, V.M., Makarov, A.A. & Vilanova, M.   "Valine 108, a chain folding initiation site belonging residue, crucial for the ribonuclease A stability.."  Biochemical and Biophysical Research Communications  265 (1999):  356-360.
    Nogués, M.V., Moussaoui, M., Boix, E., Vilanova, M. Ribó, M. & Cuchillo, C.M.  "The contribution of noncatalytic phosphate binding subsites to the mechanism of bovine pancreatic ribonuclease A.."  Cellular and Molecular Life Sciences  54 (1998):  766-774.
    Boqué, Ll., Coll, M.G., Ribó, M., Cuchillo, C.M., Fita, I. & Vilanova, M.   "Tridimensional structure of three ribonuclease A covalent derivatives with pyridoxal 5'-phosphate.."  Protein and Peptide Letters  5 (1998):  101-108.
    Matousek, J., Kim, J-S, Soucek, J., Riha, J., Ribó, M., Leland, P.A. and Raines, R.T.  "Ribonucleases endowed with specific toxicity for spermatogenic layers."  Comparative biochemistry and physiology. Part B, Biochemistry and molecular biology  118B (1997):  881-888.
    Ribó, M., delCardayré, S.B., Raines, R. T, Llorens, R and Cuchillo, Claudi M.  "Production of human pancreatic ribonuclease in Saccharomyces cerevisiae and Escherichia coli."  Protein Expression and Purification  7 (1996):  253-256.
    delCardayré, S.B., Ribó, M., Yokel, E.M., Quirk, D.J., Rutter, W. J. and Raines, R. T.  "Ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln 11."  Protein Engineering  8 (1995):  261-273.
    Bravo, J., Fernández, E., Ribó, M., Llorens, R. and Cuchillo C. M.  "A versatile negative staining ribonuclease zymogram."  Analytical Biochemistry  219 (1994):  82-86.
    Ribó, M., Beintema, J. J., Osset, M., Fernández, E., Bravo, J., Llorens, R. and Cuchillo C. M.  "Heterogeneity in the Glycosylation Pattern of Human Pancreatic Ribonuclease. ."  Biological Chemistry Hoppe-Seyler  375 (1994):  357-363.


    M. J. M. Fallon, C. Balagué, E. Fernández, M. Ribó, J. Bravo, R. de Llorens and Claudi M. Cuchillo  "Monoclonal Antibodies to Bovine Pancreatic Ribonuclease."  Structure, Mechanism and Function of Ribonucleases   (1991):  229-234.
    M. Ribó, E. Fernández, J. Bravo, M. Osset, M. J. M. Fallon, R. De Llorens and Claudi M. Cuchillo  "Purification of human pancratic ribonuclease by high performance liquid chromatography."  Structure, Mechanism and Function of Ribonucleases   (1991):  157-162.
    E. Fernández, M. Ribó, J. Bravo, M. Osset, M. J. M. Fallon, R. De Llorens and Claudi M. Cuchillo  "Isolation of secreted enzymes with ribonuclease activity from human pancreatic adenocarcinoma cell line CAPAN-1."  Structure, Mechanism and Function of Ribonucleases   (1991):  163-168.
    J. Bravo, M. J. M. Fallon, M. Ribó, E. Fernández, M. Osset, R. De Llorens and Claudi M. Cuchillo  "PHMB (p-hydroxymercuribenzoate) utilization to inactivate the inhibitor of ribonuclease in normal human pancreatic tissue and tissue culture medium from CAPAN-1 cells."  Structure, Mechanism and Function of Ribonucleases   (1991):  201-206.



    Font de les dades: Sistema d'informació GREC